E1A基因抗癌作用及其在头颈肿瘤治疗中的应用
p;products.Proc Natl Acad Sci U S
A,1990,87:4499-4503.
9 Frisch SM,Dolter KE.Adenovirus E1A-mediated tumor suppression by a c
-erbB-2/neu-independent mechanism.Cancer Res, 1995,55:5551-5555.
10 Ricardo SP,Quintanilla M,Cano A, et al.Cancinoma cell lines become
sensitive to DNA-damaging agents by the expression of the adenovirus E1
A gene.Oncogene,1996,13:1083-1092.
11 Chen MJ,Holskin B,Strickler J, et al.Induction by E1A oncogene expr
ession of cellular susceptibility to lysis by TNF.Nature,1987,330:581-5
84.
12 Steeg PS,Bevilacqa G,Pozzatti R, et al.Altered expression of nm23,a
gene associated with low tumor metastatic potential,during adenovirus
2 E1A inhibition of experimental metastasis.Cancer Res,1988,48:6550-655
4.
13 Shao RP,Karunagaran D,Zhou BH, et al.Inhibition of nuclear factor-K
B activity is involved in E1A-mediated sensitization ofradiation-induce
d apoptosis.J Biol Chem,1997,272:32739-32742.
14 Xia W,Lan YK,Zhang HZ, et al.Strong correlation between c-erbB-2 ov
erexpression and overall survival of patients with oral squamous cell c
arcinoma.Clin Cancer Res,1997,3:3-9.
15 Hou L,Shi D,Tu SM, et al.Oral cancer progression and c-erbB-2/neu p
roto-oncogene expression.Cancer Letters,1992,65:215-220.
16 Beckhardt RN,Kiyokawa N,Xi L, et al.HER-2/neu oncogene characteriza
tion in head and neck squamous cell carcinoma.Arch Otolaryngol Head Nec
k Surg, 1995, 121:1265-1270.
17 Karja V,Syrjanen S,Kataja V, et al.c-erbB-2 oncogene expression in&nb
salivary land tumors.ORL J Otorhinolaryngol Relat Spec, 1994,56:206-212
.
18 王琪，韩德民，刘鋋，等.头颈部肿瘤的P53基因研究进展.国外医学耳鼻咽喉
科学分册,1996,20：4-7.
19 Liu M,Lawson G,Delos M, et al. Expression of E-cadherin adhesion mo
lecule in vocal cord carcinomas. Eur Arch Otorhinolaryngol,1997,254:417
-421.
20 王强，郭敏，孙连玉.nm23-H1基因在喉癌组织中表达的研究.中华耳鼻咽喉科
杂志,1996,31：198-200.
21 Yu D,Matin A,Xia W, et al.Liposome-mediated in vivo E1A gene tranfe
r suppressed dissemination of ovarian cancer cells that overexpress HER
-2/neu.Oncogene, 1995,11:1383-1388.
22 Ueno NT,Hung MC,Zhang S, et al.Phase I E1A gene therapy in patients
with advanced breast and ovarian 《E1A基因抗癌作用及其在头颈肿瘤治疗中的应用(第3页)》
本文链接地址：http://www.oyaya.net/fanwen/view/147782.html
A,1990,87:4499-4503.
9 Frisch SM,Dolter KE.Adenovirus E1A-mediated tumor suppression by a c
-erbB-2/neu-independent mechanism.Cancer Res, 1995,55:5551-5555.
10 Ricardo SP,Quintanilla M,Cano A, et al.Cancinoma cell lines become
sensitive to DNA-damaging agents by the expression of the adenovirus E1
A gene.Oncogene,1996,13:1083-1092.
11 Chen MJ,Holskin B,Strickler J, et al.Induction by E1A oncogene expr
ession of cellular susceptibility to lysis by TNF.Nature,1987,330:581-5
84.
12 Steeg PS,Bevilacqa G,Pozzatti R, et al.Altered expression of nm23,a
gene associated with low tumor metastatic potential,during adenovirus
2 E1A inhibition of experimental metastasis.Cancer Res,1988,48:6550-655
4.
13 Shao RP,Karunagaran D,Zhou BH, et al.Inhibition of nuclear factor-K
B activity is involved in E1A-mediated sensitization ofradiation-induce
d apoptosis.J Biol Chem,1997,272:32739-32742.
14 Xia W,Lan YK,Zhang HZ, et al.Strong correlation between c-erbB-2 ov
erexpression and overall survival of patients with oral squamous cell c
arcinoma.Clin Cancer Res,1997,3:3-9.
15 Hou L,Shi D,Tu SM, et al.Oral cancer progression and c-erbB-2/neu p
roto-oncogene expression.Cancer Letters,1992,65:215-220.
16 Beckhardt RN,Kiyokawa N,Xi L, et al.HER-2/neu oncogene characteriza
tion in head and neck squamous cell carcinoma.Arch Otolaryngol Head Nec
k Surg, 1995, 121:1265-1270.
17 Karja V,Syrjanen S,Kataja V, et al.c-erbB-2 oncogene expression in&nb
sp;
salivary land tumors.ORL J Otorhinolaryngol Relat Spec, 1994,56:206-212
.
18 王琪，韩德民，刘鋋，等.头颈部肿瘤的P53基因研究进展.国外医学耳鼻咽喉
科学分册,1996,20：4-7.
19 Liu M,Lawson G,Delos M, et al. Expression of E-cadherin adhesion mo
lecule in vocal cord carcinomas. Eur Arch Otorhinolaryngol,1997,254:417
-421.
20 王强，郭敏，孙连玉.nm23-H1基因在喉癌组织中表达的研究.中华耳鼻咽喉科
杂志,1996,31：198-200.
21 Yu D,Matin A,Xia W, et al.Liposome-mediated in vivo E1A gene tranfe
r suppressed dissemination of ovarian cancer cells that overexpress HER
-2/neu.Oncogene, 1995,11:1383-1388.
22 Ueno NT,Hung MC,Zhang S, et al.Phase I E1A gene therapy in patients
with advanced breast and ovarian 《E1A基因抗癌作用及其在头颈肿瘤治疗中的应用(第3页)》
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