成骨细胞骨形成机制研究
3 Thies RS, Bauduy M, Ashton BA, et al. Recombinant human bone morp
hogenetic protein-2 induces osteoblastic differentiation in W-20-17 str
omal cells. Endocrinology, 1992,130:1318.
4 McCabe LR, Last TJ, Lian JB, et al. Expression of cell growth and
bone phenotypic genes during the cell cycle of normal diploid osteobla
sts and osteosarcoma cells. J Cell Biochem, 1994,56:274.
5 Owen TA, Aronow M, Shalhoub V, et al. Progressive development of
the rat osteoblast phenotype in vitro: reciprocal relationships in expr
ession of genes associated with osteoblast proliferation and differenti
ation during formation of the bone extracellular matrix. J Cell Physiol
, 1990,143:420.
6 Jane BJ, Gary SS. Osteoblast biology. In:Robert M, Davd F, Jennif
er K. eds. Osteoporosis. San Diego, California, U.S.A: Academic Press,
1996.23-59.
7 McCabe LR, Kundu BR, Harrison RJ, et al. Developmental expression
and activities of specific fos and jun proteins are functionally relat
ed to osteoblast maturation: role of Fra-2 and jun D during differentia
tion. Endocrinology, 1996, 137:4398.
8 Lynch MP, Stein GS, Stein L, et al. Apoptosis during in vitro bon
e formation. J Bone Miner Res, 19
94,9:S352.
9 Linkhant TA, Mohan S, Baylink DJ. Growth factors for bone growth
and repair: IGF, TGFβ and BMP. Bone, 1996,19:1S.
10 Schmid C, Ernst M. Insulin-like growth factors. In: Maxine G, e
ds. Cytokines and bone metabolism. CRC Press, 1992.229.
11 丁桂芝.类胰岛素生长因子对骨代谢的调节作用.中国骨质疏松杂志,1995
,1:73.
12 Kanzaki S, Hilliker S, Baylink DJ, et al. Evidence that HBC in
culture produce IGFBP-4 and -5 proteases. Endocrinology, 1994,134:383.
13 Centrella M, Horowits MC, Wozney JM, et al. Transforming growth
factor-β gene family members and bone. Endocrine Rev, 1994,15:27.
14 Hock J, Canalis E, Centrella M. Transforming growth factor beta(
TGF-beta-1) stimulates bone matrix apposition and bone cell re