补体活化与妊娠高血压综合征发病的关系
巨噬细胞的活动增加，这些物质的增高均可导致
血管内皮细胞受损,从而引起妊高征的一系列病理变化。
参考文献
1，Manuer P, Lars E. Complement in human diseases: looking towards the
21st century. Immunol Today, 1995, 16: 58-61.
2，林其德. 妊高征病因学研究的进展. 中华妇产科杂志,1997,32:3-5.
3，张斌, 庄依亮. 细胞毒性因子与妊高征. 中华妇产科杂志, 1997, 32: 49-51.
4，Hugli TE. Structure and function of the anaphylatoxins. Springer Sem
in Immunopathol, 1984, 7: 193-219.
5，Scholz W, Mcclurg MR, Cardenas GJ, et al. C5a-mediated release of in
terleukin-6 by human monocytes. Clin Immunol Immunopathol, 1990, 57: 29
7-307.
6，Haeger M, Unander M, Andersson B, et al. Increased release of tumor
necrosis factor-alpha and interleukin-6 in women with the syndrome of h
emolysis, elevated liver enzymes and low platelet count. Obstet Gynecol
, 1996, 75: 695-702.
7，Hansch G, Seitz M, Betz M. Effect of the late complement components
C5b-9 on human monocytes: release of prostanoids, oxygen radicals and o
f a factor inducing cell proliferation. Int Arch Allergy Appl Immunol,
1987, 82: 317-320.
8，Haeger M, Unander M, Bengtsson M. Enhanced anaphylatoxin and termina
l C5b-9 complement complex formation in patients with the syndrome of h
emolysis, elevated liver enzymes and low platelet count. Obstet Gynecol
, 1990, 76: 698-702.
9，Haeger M, Unander M, Bengtsson M. Complement activation in relation
to development of preeclampsia. Obstet Gynecol, 1991, 78:46-49.
10，Petrucco O, Thomson N, Lawrence J, et al. Immunofluo rescent studie
s in renal biopsies in preeclampsia. Br Med J, 1974, 1: 473- 476.
11，Tedesco O, Radillo G, Candussi
tion of terminal complement complex and S protein in normal and pre-ecl
amptic placentae. Clin Exp Immunol, 1990, 80: 236- 240.
12，尹利荣,韩吉,马鸿达,等.妊高征患者子宫、胎盘血管病变及其与妊娠结局的关
系. 中华妇产科杂志，1998，33：459-461.
13，郑英茹，陈竹钦，颜建华,等.妊高征患者血中补体活化与内皮细胞损伤关系的
研究.中华妇产科杂志，1996，31：152-155.
14，上官毕文,黄醒华,张春红,等.妊高征患者血浆中末端补体复合物的测定及其意
义. 中华妇产科杂志,1999,34: 409-411.
15，陈汉平,黄引萍,马庭元. 妊高征胎盘的免疫病理性损伤及类型. 中华妇产科杂
志,1996, 31: 540-542.
16，Gregory B.The compleme 《补体活化与妊娠高血压综合征发病的关系(第2页)》
本文链接地址：http://www.oyaya.net/fanwen/view/150202.html
血管内皮细胞受损,从而引起妊高征的一系列病理变化。
参考文献
1，Manuer P, Lars E. Complement in human diseases: looking towards the
21st century. Immunol Today, 1995, 16: 58-61.
2，林其德. 妊高征病因学研究的进展. 中华妇产科杂志,1997,32:3-5.
3，张斌, 庄依亮. 细胞毒性因子与妊高征. 中华妇产科杂志, 1997, 32: 49-51.
4，Hugli TE. Structure and function of the anaphylatoxins. Springer Sem
in Immunopathol, 1984, 7: 193-219.
5，Scholz W, Mcclurg MR, Cardenas GJ, et al. C5a-mediated release of in
terleukin-6 by human monocytes. Clin Immunol Immunopathol, 1990, 57: 29
7-307.
6，Haeger M, Unander M, Andersson B, et al. Increased release of tumor
necrosis factor-alpha and interleukin-6 in women with the syndrome of h
emolysis, elevated liver enzymes and low platelet count. Obstet Gynecol
, 1996, 75: 695-702.
7，Hansch G, Seitz M, Betz M. Effect of the late complement components
C5b-9 on human monocytes: release of prostanoids, oxygen radicals and o
f a factor inducing cell proliferation. Int Arch Allergy Appl Immunol,
1987, 82: 317-320.
8，Haeger M, Unander M, Bengtsson M. Enhanced anaphylatoxin and termina
l C5b-9 complement complex formation in patients with the syndrome of h
emolysis, elevated liver enzymes and low platelet count. Obstet Gynecol
, 1990, 76: 698-702.
9，Haeger M, Unander M, Bengtsson M. Complement activation in relation
to development of preeclampsia. Obstet Gynecol, 1991, 78:46-49.
10，Petrucco O, Thomson N, Lawrence J, et al. Immunofluo rescent studie
s in renal biopsies in preeclampsia. Br Med J, 1974, 1: 473- 476.
11，Tedesco O, Radillo G, Candussi
A, et al. Immunohistochem ical detec
tion of terminal complement complex and S protein in normal and pre-ecl
amptic placentae. Clin Exp Immunol, 1990, 80: 236- 240.
12，尹利荣,韩吉,马鸿达,等.妊高征患者子宫、胎盘血管病变及其与妊娠结局的关
系. 中华妇产科杂志，1998，33：459-461.
13，郑英茹，陈竹钦，颜建华,等.妊高征患者血中补体活化与内皮细胞损伤关系的
研究.中华妇产科杂志，1996，31：152-155.
14，上官毕文,黄醒华,张春红,等.妊高征患者血浆中末端补体复合物的测定及其意
义. 中华妇产科杂志,1999,34: 409-411.
15，陈汉平,黄引萍,马庭元. 妊高征胎盘的免疫病理性损伤及类型. 中华妇产科杂
志,1996, 31: 540-542.
16，Gregory B.The compleme 《补体活化与妊娠高血压综合征发病的关系(第2页)》
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